UKHSA Detects Polio Virus In London Sewage Samples

UKHSA Detects Polio Virus In London Sewage Samples

By Charlotte Webster-

The virus that causes polio has been detected in a concerning number of sewage samples in London, health officials have said.

The UK Heath Security Agency (UKHSA), working with the Medicines and Healthcare products Regulatory Agency (MHRA), has found polio in sewage samples collected from the London Beckton Sewage Treatment Works, which serves around four million people in north and east London. The risk is said to be low, but parents should ensure their children have been fully immunised against the disease.

While it is normal for the virus to be picked up as isolated cases and not detected again, experts have raised the alarm after several genetically-linked viruses were found in samples between February and May.

“Most of the UK population will be protected from vaccination in childhood, but in some communities with low vaccine coverage, individuals may remain at risk,” said Dr Vanessa Saliba, consultant epidemiologist at UKHSA.

An inactivated polio vaccine is used in the UK as part of the routine childhood programme. It is given to children three times before the age of one, and then again at three and 14 years of age.

Take-up of the first three doses is about 86% in London, well below target levels, with the rest of the UK over 92%.

Health authorities have now declared a national incident and informed the World Health Organization (WHO) of the situation. Over the past four months, the UKHSA has found the polio virus in samples collected from the Beckton sewage works, which serves a population of four million in north and east London.

Scientists believe the virus originated from someone who was immunised abroad with the live oral polio vaccine, which hasn’t been used in the UK since 2004.

The UKHSA is working on the theory that a person vaccinated abroad with the polio vaccine – possibly in Afghanistan, Pakistan or Nigeria – entered the UK early in 2022 and was shedding the virus.

That person has has now passed it onto other, closely linked individuals in north-east London, who in turn are shedding the virus into their faeces.

Experts are looking at the possibility that just one family or extended family may be affected, though it is unclear how many people need to be infected for polio to be detected in sewage samples.

The UKHSA stressed that the virus has only been detected in sewage samples and no cases of paralysis have been reported.

It is now investigating the extent of community transmission and has established a “national incident” to check for cases elsewhere as a precaution.

The polio vaccine is given on the NHS when a child is eight, 12 and 16 weeks old as part of the 6-in-1 vaccine. It is given again at three years and four months old as part of the 4-in-1 (DTaP/IPV) pre-school booster, and at 14 as part of the 3-in-1 (Td/IPV) teenage booster.

All of these vaccines need to have been given for a person to be fully vaccinated, though babies who have had two or three doses will have substantial protection.

That person then shed traces of the virus from their gut which were detected by the sewage sampling.

In rare cases, that form of the virus can then be transmitted to others and mutate into what is known as “vaccine-derived” polio.

Although weaker than the original or “wild” form of the disease, it can still cause serious illness, including paralysis, in people who are unvaccinated.

A small number of samples of the polio virus are detected each year in sewage surveillance, but this is the first time that a cluster of genetically-linked samples has been found repeatedly over a period of months.

Health officials say this suggests there has been some spread between closely linked individuals in London.

No actual cases of polio have been detected and there have been no reports of rare but serious symptoms in the UK.

He added that he had been reminded by the UK’s Health and Security Agency that the UK has a high vaccination rate against the virus, with no cases since 2003.

Jane Clegg, chief nurse for the NHS in London, said the health service would be contacting parents of children aged under five in London who are not up to date with their childhood jabs.

“Parents can also check their child’s vaccination status in their red book, and people should contact their GP practice to book a vaccination should they or their child not be fully up to date,” she said.

Polio is a rare disease and is spread after a person does not wash their hands properly after using the toilet and then touches food or water consumed by others, or in rarer cases by coughing and sneezing.

Most people don’t have any symptoms and will fight off the virus without even realising they were infected. A small number will experience flu-like symptoms for up to three weeks.

In a very small number of cases, thought to be between one in 100 and one in 1,000, the polio virus attacks the nerves in the spine and base of the brain.

This can cause paralysis, usually in the legs. If the breathing muscles are affected, it can be life-threatening.

 

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