By Charlotte Webster-
Scientists have developed a novel way of editing genes in a way that can convert fat cells to energy cells.
In an interesting development, a group of researchers from UT Southwestern Medical Centre’s Touchstone say they can use gene editing to turn fat into energy cells.
The research which was supported by the National Institutes of Health was added to previous research by the same tam in 2016 called Cell Metabolism. The latest findings were published in Genes and
According to Dr Gupta, people with obesity have few brown and beige fat cells, which are those that help burn energy, whereas they have larger numbers of white cells and of a bigger size, cells of which store energy. Brown cells aid against the possibility of diabetes of cardiovascular diseases formulating.
”There is tremendous interest in driving the production of these energy-burning fat cells as a treatment against metabolic diseases such as diabetes,” said Dr. Gupta, who called obesity “the pandemic before the pandemic.”
Two main types of fat cells exist in people—white cells that serve as the site of energy storage and expand in number and size in those with obesity, and energy-burning brown and beige cells that burn excess energy to produce heat and increase energy expenditure.
Rana Gupta, associate professor of internal medicine PHD told Medical Express
that engineering a mutation that disrupts the interaction of cells
Researchers have long been keen to understand ‘all aspects of adipose tissue biology’ and how the body forms fat cells, Dr Gupta said.
Dr Gupta is convinved the discovery could be the first step in addressing fast cells could aid diabetes and other metabolic diseases.
Researchers later discovered that ‘existing diabetes medications’ can possibly be made much more effective by ‘releasing this brake in fat calls’.
According to Dr Gupta, people with obesity have few brown and beige fat cells, which are those that help burn energy, whereas they have larger numbers of white cells and of a bigger size, cells of which store energy. Brown cells aid against the possibility of diabetes of cardiovascular diseases formulating.
The rise of obesity has put pressure on researchers to understand ‘all aspects of adipose tissue biology’ and how the body forms fat cells, Dr Gupta said.
If you’ve been affected by any of the issues in this article and would like to speak with someone in confidence, call the BEAT Eating Disorders helpline on 0808 801 0677. Helplines are open 365 days a year from 9am–8pm during the week, and 4pm–8pm on weekends and bank holidays. Alternatively, you can try the one-to-one webchat.